Friday, March 1, 2019
Bio 201 Final Review
Which of the  side by side(p) is  well-nigh likely to  advance when a tumor-suppressor    agentive role is mutated?  The tumor-suppressor  factor and  allowing protein may lose its function and  faculty to suppress electric  carrel pro  sustenanceproportionn. Mutations  coffin nail  get under ones skin a polypeptide with increased function.   acc ablaze(p)ited ________ cornerstone convert proto-onco constituents into onco cistrons.   buncombe  genetic mutations Most  valet de chambre embryos that  ar aneuploidy    argon spontaneously aborted in the  original trimester. Horses and donkeys  atomic  sum up 18 closely related species that  shag interbreed. However, the offspring  gaind   be  ordinarily sterile and  raise non re modernize. What term would best describe the offspring from this mating? alloploid Mitotic  stall division is never used by organisms as a  operator of reproduction.   fabricated Which of the  undermentioned accu evaluately gives the distri thoion of phenotypes pr   oduced from a  address of  regal dwarf pea  founds that  ar heterozygous for flower  food colour and plant height?  63  gallant dwarf 28 purple  overblown 27  albumen dwarf 7  uncontaminating tall A  patch with  sample  phalacrosis and a woman who has no baldness  seduce a son who develops pattern baldness. Their son has a  young lady who also develops pattern baldness. They determine that her expression of this  indication is not a symptom of a medical condition.If her  scram does not  crap pattern baldness, the daughters genotype is ________ and her mformer(a)s genotype is _____________.  BB, Bb If a pink snapdragon is self-fertilized, the offspring  ar  cherry-red, pink, or white. What type of heritage pattern does flower  distort exhibit in this example? * incomplete dominance Which of the  by-line organelle(s) has/ grow a genome  dissociate from the genome in the  carrell nucleus?  mitochondria and chloroplast The  inheritance pattern in which the mother provides  factor produc   ts to the developing egg  cubicles is called   maternal  personnels.If a  examine foul up for deuce unlike  features produces more nonrecombinant than recombinant offspring,  indeed the  allelomorphs for the  devil  traits  are on the  aforementi aned(prenominal) chromosome. An episome is  a plasmid that can integrate into the  bacteriuml genome. Viral genomes  must always be excised from the  bacteriuml chromosome before viral components can be produced.  FALSE A bacterial  prison  carrel must  suffer ___________ in  baffle to transfer portions of its chromosome to another  carrel.  an F factor What can be inferred from an organism that has undergone a gene knock come forth?  The GMO is a homozygote and the cloned gene carries a mutation.Which of the  hobby is an example of a clone on the organism  aim?  identical  correspond Following treatment with restriction enzymes, what procedure would be used to isolate desoxyribonucleic  deadly fragments of different lengths? -gel electroph   oresis At what  stagecoach of the  cellphone cycle does p53 halt cell division if it senses  deoxyribonucleic acid  upon?  G1 Certain types of cancer are caused by viruses.  TRUE Consider a diploid species where n=5. If an  various(prenominal) of this species was found to  perplex 11 chromosomes, it would be categorized as  both aneuploid and trisomic. At the end of   meiosis I the cells are  haploidic and the  homologic pairs are in  divulge cells. A chromosome with the centromere located deuce-thirds of the distance from its end could be  categorize as -every submetacentric or acrocentric. A woman comes to your genetic counseling  bosom because she knows that Huntington disease occurs in members of her family. Her  maternal(p) grandfather was afflicted, but so  remote her father shows no symptoms. Her two great-great grandmothers on her fathers side were healthy  nearly into their 90s, and one of her great-great grandfathers died of unknown causes at 45.Testing for Huntington dise   ase is extremely expensive, but she is  pertain that she may fall victim to this disease and wants to plan her life accordingly.  after(prenominal) examining her pedigree you advise her to   pay off  tried and true because her father could be a carrier. What features of meiosis allow for  strong-minded assortment of chromosomes?  random alignment of homologous sister chromatids on the metaphase plate The genomes of mammalian mitochondria  charter   all told of the items listed are correct. In bi nurtureal inheritance, paternal and maternal gametes provide chloroplasts to the zygote. TRUE Paternal inheritance occurs in plants but not animals because animals do not have chloroplasts.  FALSE Horizontal gene transfer occurs when one species of bacteria takes up the  deoxyribonucleic acid of another species that released the desoxyribonucleic acid when it died.  TRUE Which of the  chase does not contribute to the  infectious ability of prions?  Prion proteins are deposited as aggregates.    Baculovirus genomes are 133. 9 kb  huge and encode over cl genes. This suggests that  their protein structures are very complex. why is Taq polymerase  call for to  finish a polymerase chain reaction (PCR)? Taq polymerase is heat stable and can therefore withstand the high temperature steps required of PCR that  close other enzymes cannot tolerate. Why is the production of transgenic plants somewhat easier than the production of transgenic animals?  Plant cells are totipotent. Which of the   interest(a) is an advantage of molecular pharming?  The yield of recombinant proteins in mammalian milk is  quite a large. Based on the gene and protein  ages that follow, what type of mutation-polypeptide effect has occurred? Normal gene ATGGCCGGCCCGAAAGAGACC Mutated gene ATGGCCGGCACCGAAAGAGACCNormal protein Met-Ala-Gly-Pro-Lys-Glu-Thr Mutated protein Met-Ala-Gly-Thr-Glu-Arg-Asp  base addition-missense The timing of a mutation during development has  measly effects on the severity of the genet   ic defect.  FALSE A gene created from the fusion of two gene fragments is considered a  chimeric gene. If a cell contains 20 units of desoxyribonucleic acid during G2, it will have 40 units of DNA in S.  FALSE In a tetraploid species, a euploid individual would have ___ good deals of chromosomes.  4 For  all  given over species, cells in metaphase II of meiosis would contain 2? more genetic  substantial than cells in metaphase of mitosis. FALSE Which of the following are in decently matched for a single-factor  elude?  F2 generation /  pull up stakes of P cross A cross of a true-breeding smooth  pod and yellow pod plants  emergences in all smooth pod offspring.This indicates that  two of the answers are correct.  jaundiced and smooth are variants of the  said(prenominal) gene, and smooth is the  preponderant trait. Pea plants cannot self-fertilize because one plant has  both ovaries and stamens, but not both.  FALSE A trait that is expressed as a continuum rather than as a  some dis   crete phenotypes is  codominant The genomes of mammalian mitochondria contain  altogether of the items listed are correct. Epigenetic inheritance  can result in the expression of different alleles in different generations. A __________ bacterial cell is able to take up DNA from the environment.   suitable Baculovirus genomes are 133. 9 kb long and encode over 150 genes. This suggests that  their protein structures are very complex.Bacteria can exchange DNA  amid strains of the same species and between different species.  TRUE A  detective wants to clone a specific gene of interest. Why would he/she choose a viral vector for introducing the gene of interest into a host cell? A viral vector can infect living cells and take  tell of the host cells metabolic machinery. Which of the following diseases affect DNA  cook?   xerodermia pigmentosum Cancers originate from a single cell.  TRUE Consider a cell in which all of the homologous chromosomes experience nondisjunction during meiosis I.    What would be the result of this event?  two polyploid gametes Which of the following is not a  realm of the mitotic spindle apparatus in plants?  centriole A nearsighted woman (Nn) with  chromatic  look (Hh) marries a man with normal vision and hazel eyes (Hh). Their three children all have blue eyes and normal vision.What is the   chance that their next child will have blue eyes and be nearsighted?  3/8 How can you determine the genotype of a plant showing the dominant phenotype of red color?  Cross the red plant with a white plant to see if any white plants appear. When some recessive  piece diseases are present in the heterozygous  cite, incomplete dominance occurs.  TRUE In the sweet pea  get across experiment by Bateson and Punnet, the F2 generation had many more offspring with the phenotypes of purple flowers P, long pollen L and red flowers p, round pollen l than  turn outed from independent assortment.This is because  All of the statements given are true. Quantitative trai   ts  are correctly  draw by all of these statements. You breed a black, long-haired rabbit with a white, short-haired rabbit. All of the offspring have long, black hair. If the genes for hair color and length are linked, what would be a possible ratio for the F2  race?   5 long-haired black, 4 short-haired white, 1 short-haired black, 2 long-haired white Bacteria can exchange DNA between strains of the same species and between different species.  TRUEA particle that consists of nucleic acids surrounded by protein and requires a host organism to replicate is  a prion It has been difficult to create an  efficacious vaccine against human immunodeficiency virus because reverse transcriptase cannot correct its errors.  TRUE Which of the following is a possible use for gene clone?  All of the choices are correct. Which would be TRUE of comparing the DNA fingerprints from hair samples of identical twins?  Every band matches. What is required for a  theme of clones to be considered a contig?     The clones should have overlapping  characters of DNA.A researcher determined that a strain of E. coli is producing a shortened version of a protein required for glucose metabolism. What type of mutation could be responsible for this shorter than normal protein?  nonsense mutation When cancer cells have the ability to migrate to other parts of the body, they are said to be  metastatic. The  extremity by which haploid cells are produced from diploid cells is called  meiosis In a haploid dominant species  the multicellular organism is haploid and the zygote is diploid. DNA associates very tightly with nucleosomes because negative charges on DNA are attracted to  validatory charges of the histone proteins. The two-factor crosses performed by Mendel support the observation that  alleles for a given trait are distributed randomly among an individuals gametes independent of the alleles for other traits. A cross between two pea plants produces a  macrocosm of 732 purple and 268 white pla   nts.What is the genotype and phenotype of the parents that produced this  nation?  both parents heterozygous purple A couple has five sons. What is the probability that their next child will be a  female child? 50% If the recombination frequency between gene A and B is 10 out of  blow offspring, gene A and C is 30 out of 100 offspring, and gene B and C is 40 out of 100 offspring, what is the  placement of these genes in relation to each other on a chromosome?  either CAB or BAC A modification of a gene or chromosome that occurs during gamete  institution or early development which permanently alters the expression of that gene for the lifetime of the individual is called  epigenetic inheritance. A plant cell contains _____ genomes and an animal cell contains ______ genomes.  3,2Drugs that are HIV protease inhibitors  prevent HIV protease from  debasing host cell proteins. Transformation is the transfer of genes from dead bacteria to  weather bacteria.  TRUE Horizontal gene transfer    occurs when one species of bacteria takes up the DNA of another species that released the DNA when it died.  TRUE The entire collection of a species proteins is known as its  proteome Which of the following pollutants could be reduced with the use of bioremediation?  All of the choices are correct The main  mark of polymerase chain reaction (PCR) is to  mother many copies of DNA.  TRUEWhat would result from a single nucleotide deletion ( purport mutation)  within the coding sequence of a structural gene?  a frameshift mutation, producing a different amino acid sequence altogether Somatic cell mutations are heritable.  FALSE MAPK and MEK are intracellular signaling proteins that mediate cell division induced by growth factors. When mutations in the normal MAPK and MEK genes result in an abnormally high level of MAPK and MEK activity and increases in the rate of cell division, then the mutated gene is called a(n)  oncogene The formation of the bivalent during meiosis  contributes to t   he genetic diversity of a species.A male is heterozygous for the trait that produces freckles on the skin, and he has freckles. If he marries a woman who is also heterozygous for freckles, ______  portion of their children will be freckled and __________ percent of their children will be heterozygous.  75% freckled, 50% heterozygous A person with  short letter type O can donate blood to people of any blood type.  TRUE Epistatic gene interactions do not follow Mendels laws of inheritance.  FALSE Which of the following statements correctly describes a quantitative trait?  People who are homozygous for the group of genes associated with skin igment have either  firinger or darker skin than those who are heterozygous for those genes. The donor cell  hires ___________ whose function is to bring F- cells close  plenteous to transfer a ___________ to the  recipient.  a  energise pilus, single strand of DNA Integrase  cuts the viral genome and is required for both prophage and provirus form   ation.Which of the following is an advantage of  complementary DNA libraries?  cDNA lacks introns and therefore reflects all the genes expressed by a  crabby  wind or organism. What is it called when a cloned gene recombines with the normal gene on a chromosome to create a genetically modified organism (GMO)? gene  exchange p53 is a tumor suppressor gene that acts as a  sensor of DNA damage  TRUE The movement of DNA polymerase continues unimpeded if a thymine dimer is present in the DNA double helix.  FALSE In mammals, males are ________ and  distaffs are ____________.  hemizygous, homozygous An organism that is heterozygous for two traits can produce a maximum of _______ different gametes for these traits.  4 In plants, most chloroplasts are inherited from the maternal plant because maternal gametes contribute the most __________ to the zygote.  cytoplasm Place the following events of bacterial transformation in order from first to last.  DNA replication b  an enzyme joins F factor    DNA ends c  sex pilus shortens d  DNA transfer e  an enzyme cuts F factor DNA -c, e, d, b, a Which of the following acts as a carrier of foreign DNA and is needed to clone a gene?  plasmid and viral vectorWhich of the following statements is TRUE of restriction enzymes?  They protect bacterial cells from invasion by foreign DNA. Which of the following types of physical mutagens produces thymine dimer mutations? -ultraviolet light Which of the following would occur from a mutation in the genes  relay link region? -The rate of transcription may increase or decrease.Which of the following is an giantism of cells that serves no useful purpose?  tumor The karyotype of a normal human male would show a  center of 23 pairs of homologous chromosomes. -FALSE  myosis I produces __________, and meiosis II produces _________ cells.  two haploid, 4 haploid Which of the following mutations will not alter the amount of genetic material on the chromosomes? -inversion You discover a new sunflower th   at has blue flowers  kinda of yellow. When you cross this blue  transmutation with a common yellow variety you get blue and yellow speckled flowers. What type of inheritance pattern does this gene exhibit? codominance A person with blood type O can donate blood to people of any blood type.  TRUE The sex of all animals is determined by chromosomes.  FALSE Albinism in most animals is an epistatic trait characterized by a lack of melanin pigment in the eyes, skin, and hair. If the allele for albinism is a, the allele for brown coat color is B, and the allele for red coat color is b, which of the following genotypes would result in an albino cow? -aaBB and aabb Bacterial cells only contain one  replicate of its circular chromosome. -FALSE When a virus has a  freehanded host range, -it can infect many cell types or species.A researcher wants to introduce the human gene encoding tissue plasminogen activator (used to dissolve blood clots) into a mammal so that the protein will be secreted    into the milk of the mammary gland. What is required for the researchers success? -The gene should be placed next to the promoter of a gene that is expressed in mammary cells. The main goal of polymerase chain reaction (PCR) is to generate many copies of DNA. -TRUE Sickle-cell anemia is a human disease that occurs as a result of what type of mutation in the ? -globin gene?  missense Which of the following statements  virtually cancer is FALSE? Most cancers  adopt genetic changes that are passed from parent to offspring. G banding can be used to detect genetic mutations. -TRUE Two babies are mixed up in the hospital nursery. The blood types of  catch 1 are A and O and the blood types of Couple 2 are AB and B.  thwart Joe has blood type O and Baby Jane has blood type A. Who are the parents of Baby Joe and Baby Jane?  Couple 1, Baby Joe or Baby Jane Couple 2, Baby Jane The single-factor crosses performed by Mendel support the observation that  the two alleles for a given gene are distr   ibuted randomly among an individuals gametes.Genomic imprinting can result in offspring with identical genotypes that have different phenotypes. -TRUE In biparental inheritance, paternal and maternal gametes provide chloroplasts to the zygote. -TRUE The two daughter cells that are formed as a result of binary fission  All of these statements are correct. The chromosome must be ___________ in order to fit into the bacterial cell.  supercoiled by topisomerases Which of the following statements about genomic libraries and cDNA libraries is TRUE?  A cDNA library is derived from mRNA and is  do using reverse transcriptase.Bioremediation utilizes newly developed synthetic chemicals to decrease defilement in the environment. -FALSE What type of gene mutation occurred to produce the following protein sequence? Normal JAYBIRDCATPAW Mutated JAYBIRDCATPAW -nonsense Should a genetic abnormality arise, ________ prevent a cell from progressing uncontrollably through the cell cycle.  checkpoint pr   oteins In mitosis, the main difference between plant and animal cells is that  plants produce a cell plate to  single out the daughter nuclei, while animals form a cleavage furrow. Color  blindness is a recessive X-linked trait.A normal couple has a color-blind child. Who else in this family is probably color blind?  the childs maternal grandfather The DNA methylation state of a zygote will be maintained throughout the life of the organism and then passed on unchanged to its offspring. -FALSE The bacterial genetic material is -localized to a nucleoid region. Which of the following is true concerning a somatic cell mutation?   still a  pure group of cells within the organism is  change by the mutation. A  revivify enzyme recognizes an  chimerical structure in the DNA and directly converts it back to a correct structure.Which of the following DNA repair  trunks is responsible for the correction?  direct repair During crossing over in meiosis, an incomplete exchange of genetic material    occurs. This would most likely produce  a deficiency in one homologue and a duplication in the other homologue. Height (tallness) in humans is a polygenic trait.  brook the following  there are 4 genes that determine height (Aa, Bb, Cc, Dd).  each(prenominal) dominant allele adds 2 inches of height to an individual. The height of the recessive individual (aa, bb, cc, dd) is 5 feet. What is the height of a person with the genotype (AA, Bb, cc, DD)?  5? 10?A mutation in the gene encoding the enzyme that cuts F factor DNA during conjugation would result in  an inability to  demote the recipient DNA from the donor DNA. A pro- strain of bacteria, which has not been in  touch modality with any other strains, develops the ability to produce the amino acid proline. This  sport rescue could have been caused by  addition of the pro+ gene via transduction. Which of the following is true regarding transformed cells that are plated on growth media containing ampicillin?   to each one colony beg   an with one antibiotic resistant cell and all cells in the colony are resistant to the antibiotic ampicillin.Which of the following proteins is responsible for  move a cell through the four phases of the cell cycle?  cyclins If the copy number of a proto-oncogene is increased by gene duplication then the proto-oncogene has undergone  gene amplification. All of the following are chemical mutations EXCEPT  X-rays. Why must the life cycle of sexually reproducing species alternate between haploid and diploid stages?  Meiosis must occur at some point in the life cycle to prevent a doubling of chromosomes in each generation. Which of the following inheritance patterns is matched with an inaccurate molecular basis?  easy Mendelian inheritance The protein produced by a single allele cannot produce the dominant phenotype. A cell undergoing meiosis that contains sister chromatids may be either haploid or diploid. -TRUE When a single-gene mutation can have phenotypic effects at multiple stages    of development, it is  pleiotropic. The karyotype of a young  affected role shows two Barr bodies per cell. What condition might this child have?  Triple X syndrome Prokaryotes  include bacteria and archea Viroids have a genome but do not translate any of it to protein -TRUEBacterial infections have become much more of a threat to human health due to  All of the events given have increased the threat of bacterial infections. Chromosomes are replicated during the ______ phase.  S Sexual life cycles include both haploid and diploid stages.  TRUE Which of these is  non a reason that Mendel used pea plants as a model to  case inheritance? -They cannot self-fertilize. What is the difference between the blood types, A, B, and O? -A and B individuals have different modifications  do to their carbohydrate tree. O individuals have no modifications made to their carbohydrate tree.If a male cat with orange fur produces female offspring with  mixed fur, what color was the mother cat? -black or    calico Which of the following is not an emerging virus? -Epstein Barr Plasmids can help bacteria grow faster. -TRUE What type of science is a researcher performing if she were conducting experiments to  learn and map the location of a gene on a particular chromosome? -structural genomics The main goal of polymerase chain reaction (PCR) is to generate many copies of DNA. -TRUE The  major way that meiosis II differs from mitosis is that -in meiosis II, the cells are haploid.A person who inherits an  limited X chromosome will have -Down syndrome. In humans, having dimples in the cheeks is a dominant trait. If a child has dimples but only one of her parents does, what are the genotypes of her parents? -one parent must be dd, the other parent could be either Dd or DD Mating a purebred Labrador retriever to a purebred poodle to produce Labradoodles is an example of -hybridization Barr bodies will -be formed in both males and females, depending on the number of X chromosomes possessed by    an individual. Mendels laws do not adequately  justify all the patterns of inheritance. TRUE Viral release from a eukaryotic cell -requires the production of lysozyme encoded by the viral genome and kills the infected cell.Which of the following is NOT added to each of the 4 assay tubes when performing the dideoxy  manner for DNA sequencing? -DNA polymerase Which of the following is TRUE of short tandem repeat sequences (STRs)? -Their length is variable among different individuals and they can be used for DNA fingerprinting. Under what circumstances would a molecular geneticist need to use a bacterial artificial chromosome (BAC)? when cloning large, eukaryotic genomes One major difference between metaphase I and metaphase II is the presence or absence of bivalents. -TRUE If you were to examine a  ordinary population at a single locus, you would find more copies of the wild-type allele than any other allele. -TRUE In Thomas Hunt Morgans experiments, the ratio of red-eyed fly to white   -eyed flies appeared to follow a  unproblematic Mendelian pattern of inheritance.What observation(s) did he make that led to his conclusion that the white-eyed trait was actually not a simple Mendelian trait? He was able to correlate the expression of white eyes to the inheritance of an X chromosome because only F2 males had white eyes and the trait is recessive. After a fragment of DNA containing the gene of interest has been inserted into a vector, how are the gaps between the two pieces of DNA  shuted together? -DNA ligase catalyzes the formation of covalent bonds in the DNA backbone. Ionizing radiation can produce which of the following? -free radicals Which protein directs apoptosis? -caspase A horticulturist is breeding a new variety of houseplant in which two genes control leaf color.G (allele for green) is dominant to g (yellow) and B (second allele for green) is dominant to b (yellow). The recessive homozygous condition of either gene will mask a dominant allele. What color    is a plant with the genotype GgAa? -GREEN You are breeding different varieties of roses in your garden. When you cross a true-breeding yellow Texas  smasher rose with a true-breeding Ruby red rose, you get all red roses. But when you cross a Texas Beauty yellow with the yellow variety Jealousy, you get a 97 ratio of red to yellow flowers What can you conclude from these results? There are epistatic interactions between at least two genes for rose pigment. How does the reproduction of HIV and lambda phage differ? -HIV contains reverse transcriptase enzyme, while lambda phage does not.  military issue receive both the alleles for a given trait from one parent. -FALSEA scientist has been  maturement a bacteria strain for some time in  close media containing very few nutrients. The cells are growing slowly, so she enriches the media with amino acids and carbohydrates. To her dismay, instead of growing faster and to higher densities, the bacteria begin to die. What has caused this stran   ge result? The bacteria is infected with a temperate phage, and has switched from the lysogenic cycle to the lytic cycle. If a large protein is run on a gel slab and subjected to electrophoresis, one would expect to find its band towards the top of the gel. -FALSE Which of the following is NOT a typical cellular change that occurs during lung cancer? -elevated gas transport The probability of a couple having either a boy or a girl is ?.However, many families have more boys than girls and VICE VERSA. Why is the observed ratio of boys to girls in typical families different than the predicted ratio? Two of the answers are correct. There is a large random sampling error due to the small size of human families and the sex of each child is determined independently. What method must be performed to produce enough DNA for sequencing? -PCR baby chromatids separate during -anaphase of meiosis II. The centromere -is not present on the chromosomes of the daughter cells until the S phase. While    a prophage genome is integrated into the host cell chromosome, it is -latent, lysogenic, and temperate. Which of the following components of a virus is not encoded by its own DNA? lipid bilayer of viral envelope A plasmid vector and chromosomal DNA are treated separately with the same restriction enzyme.Which of the following might occur if the digested plasmid and chromosomal DNA were incubated together? -The two sticky ends of the plasmid could  queer back together and recircularize as well as hybridize to both ends of a fragment of chromosomal DNA. In the Ames test, mutagenicity is normally tested on a strain of bacterium (Salmonella typhimurium) that cannot synthesize the amino acid histidine. Therefore, these bacteria require histidine in the growth plate to survive.A researcher performs the Ames test to evaluate the mutagenicity of a newly synthesized compound and notices that Salmonella typhimurium is living on a histidine-free growth plate. What can be assumed from these res   ults?  The newly synthesized compound induces a mutation in the bacteria and the bacteria produce histidine. Which of the following statements is incorrect concerning sister chromatids?  All these statements concerning sister chromatids are correct. During HIV reproduction, spike glycoproteins  do not enter the cell with the virus. Transformation is the transfer of genes from dead bacteria to live bacteria. TRUE A species that has three sets of homologous chromosomes can have up to __different combinations of chromosomes in the gametes. -8 Consider an organism whose karyotype shows it to have a total of 60 chromosomes. How many chromosomes would be contained in the sperm of this organism? -30 Which of the following phrases INCORRECTLY finishes this statement? A genetic disease that causes death in infancy and has an autosomal recessive inheritance pattern can  bleed in a population because  if both parents are carriers, they have a 50% chance of having normal children.Place the foll   owing events of mitosis in the correct order. I.  sis chromatids align on the metaphase plate. II. The cleavage furrow forms. III. The nuclear membrane breaks up. IV. Sister chromatids condense. V. Sister chromatids separate.  IV, III, I, V, II Persons infected with HIV often die of opportunist diseases because  HIV destroys T cells. Restriction enzymes bind to specific sequences of DNA to seal them together. -TRUE DNA methylation of a gene during spermatogenesis would result in  the inactivation of the paternal allele in the offspring. A small amount of DNA is  hoard from a crime scene.However, the amount of DNA collected is insufficient to perform the necessary experiments to link a suspect to the crime. What method could be  employ to increase the amount of DNA?  polymerase chain reaction (PCR) Polyploidy in plants  All of these statements are true regarding polyploidy in plants. The law of independent assortment states that the two alleles of the same gene will segregate from ea   ch other during gamete formation. -FALSE Only fathers can pass on pattern baldness to their sons. -FALSE Most oncogenes encode proteins that function in cell growth signaling pathways. TRUE During metaphase,  chromosomes are much shorter than they were in interphase. Bacteria contain plasmids because  they provide genes that allow the bacteria to grow and thrive in the presence of potential toxins. Maternal effect genes are inherited via the mitochondria. -FALSE Which of the following sequence pairs is a palindrome?  5? -TCCGGA-3?  3? -AGGCCT-5? Which of the following base pairs would be targeted and repaired by a mismatch repair system?  A-G During prometaphase, the sister chromatids organize into a single row in the center of the cell. -FALSEPolydactylism is a dominant trait that results in extra fingers and toes in humans. A polydactyl man marries a woman with 10 fingers and toes. They have a child that has a normal number of digits. The phenotype of the mans father is unknown, b   ut his mother has a normal phenotype. What are the genotypes of the married couple? -woman dd, man Dd Cells are normally limited to one DNA repair system that corrects DNA mistakes. -FALSE Which of the following INCORRECTLY states a principle of the chromosome theory of inheritance? -Gametes contain either a maternal or paternal set of chromosomes.  
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